1、 分子细胞生物学Molecular CELL BIOLOGY主讲教师：丁明孝，陈建国，张传茂Chapter 1 Introduction to the cellLearning Objectives1.About Cell Biology2.Look briefly at the history of cell theory;3.Consider the basic properties of cells;4.Compare some characteristics of two different classes of cells:prokaryotes and eukaryotes;5.C
2、omprehend a special life: viruses1. About “Cell Biology”What?Forwhy?How tostudy?The NIH of USA(1988):“What is popular in research today ？ ” 3 kinds of diseases ： cancer cardiovascular diseases infectious diseases： AIDS， hepatitis 5 research fields ： cell cycle control ； cell apoptosis； cellular sene
3、scence； signal transduction； DNA damage and repair.What we know/How we know .ISI, USA(1997) : SCI（ Science Citation Index） Papers:Three tops of research fields: No1: Signal transduction；No2: Cell apoptosis；No3: Genome and post-genomic analysis。2. The Cell Theory: A Brief HistoryIn 1665, Robert Hooke
4、 saw a network of tiny boxlike compartments that reminded him of a honeycomb. He called these little compartments “cellulae”, a Latin term meaning little room. It is from this word we get our present-day term, cell. The microscope used by Robert Hooke and the honeycomb-like network of “cell” he draw
5、ed in 1665The discovery of cells followed from the invention of the microscopeCell theory has three basic tenets:1. All organisms are composed of one or more cells.2.The cell is basic unit of structure and function for all organisms.3.All cells arise only from preexisting cells by division.3. Why ar
6、e cells the basic units of life?A. The cell is the structural unit of life, All organisms is make up of cells.B.The cell is the functional unit of organisms. All metabolic activity is based on cells. C. The cell is the foundation of reproduce, and the bridge of inheritance. D. The cell is the growin
7、g and developing basis of lifeHuman fetal development . (a)At 5 weeks, limb buds, eyes, the heart, the liver and rudiments of all other organs have started to develop in the embryo, which is only about 1cm long. (b)Growth and development of the offspring, now called a fetus, continue during the second trimester. This fetus is 14 weeks old and about 6cm long. (c)The fetus in this photograph is 20 weeks old. Now the fetus grows to about 30cm in length.
