Chronic Renal FailureChronic Renal Failure陆福明陆福明复旦大学附属华山医院肾脏科复旦大学附属华山医院肾脏科The importance of Chronic The importance of Chronic Renal FailureRenal Failuren nWorldwide,the prevalence of CRF is increasing by more than 5%annuallyn nThe cost of renal replacement therapy has an increasing impact on health economics in both developed and developing countriesPlasma Plasma CreatinineCreatinine and and GFRGFRn nNormal GFR 100-125ml/min/1.73m2n nGFR declines by about 1ml/min/1.73m2/yearn nPlasma creatinine