厚 德 博 爱 精 医 卓 越Therapeutic Strategy of Antibiotic to Severe Infection厚 德 博 爱 精 医 卓 越Therapeutic Strategy of Antibiotic to Patients with Severe InfectionInitial empirical therapy VS.Targeted therapyDown-ladder therapeutic strategy:is a anti-infective protocol of empirical therapy has two characteristics as following:use a single,broad-spectrum,potent antibiotic at the beginning of anti-infective therapy,try to cover the pathogenic bacteria;afterward(48 to 72 hours),based on microbiological and su