关节软骨损伤正常关节软骨v病理基础:透明软骨结构:4层。表层、中间层、柱状层、钙化软骨、软骨下骨。(有清楚的潮线)胶原成分:型胶原基质成分:葡糖醛胺(硫酸软骨素、硫酸角质素等),水分。透明软骨的成分 v水 65-80%v基质 晶体样网状结构 (lattice-type framework)胶原 II V IX X XI 蛋白聚糖(proteoglycans)v软骨细胞(chondrocyte)分泌基质不能再生Lattice-like position功能单位(functional organization unit)v切线区 tangential zonev中间区 intermediate zonev钙化软骨 calcified cartilage v潮线 tidemarkOrganization of the cartilage unithistology of group 2In group 2,the result was close to that of normal cartilageIn group 2,the result was close to that of nor