世界卫生组织国际癌症研究机构致癌物清单.doc

1、世界卫生组织国际癌症研究机构致癌物清单1 类致癌物清单（116 种）1 类致癌物：对人类为确定致癌物。序号 英文名称 中文名称确定时间（年）1Acetaldehyde associated with consumption of alcoholic beverages随酒精饮料摄入的乙醛 20122Acheson process, occupational exposure associated with艾其逊法(用焦炭和粘土混合加热制造石墨的工业方法)，职业暴露相关20173 Acid mists, strong inorganic 强无机酸雾 20124 Aflatoxins 黄曲霉毒素

2、20125 Alcoholic beverages 酒精饮料 20126 Aluminium production 铝产品 20127 4-Aminobiphenyl 4-氨基联苯 20128 Areca nut 槟榔果 20129 Aristolochic acid 马兜铃酸 201210Aristolochic acid, plants containing包含马兜铃酸的植物 201211Arsenic and inorganic arsenic compounds砷和无机砷化合物 201212Asbestos (all forms, including actinolite, amosi

3、te, 铁石棉,石棉(各种形式,包括阳起石直闪石 ,温石棉,青石棉、透闪石)2012anthophyllite, chrysotile, crocidolite, tremolite)13 Auramine production 金胺制造 201214 Azathioprine 硫唑嘌呤 201215 Benzene 苯 201216 Benzidine 对二氨基联苯 201217 Benzidine, dyes metabolized to 联苯胺、染料代谢 201218 Benzo a pyrene 苯并芘 201219Beryllium and beryllium compounds铍和

4、铍化合物 201220 Betel quid with tobacco 含烟草的槟榔嚼块 201221 Betel quid without tobacco 不含烟草的槟榔嚼块 201222Bis(chloromethyl)ether; chloromethyl methyl ether (technical-grade)二氯甲基醚;一氯甲基醚(技术等级) 201223 Busulfan 白消安 201224 1,3-Butadiene 1,3-丁二烯 201225Cadmium and cadmium compounds镉及镉化合物 201226 Chlorambucil 苯丁酸氮芥 201

5、227 Chlornaphazine 萘氮芥 201228 Chromium (VI) compounds 铬(VI)化合物 201229 Ciclosporin 环孢素 201230Clonorchis sinensis (infection with)华支睾吸虫(感染) 201231 Coal gasification 煤的气化 201232Coal, indoor emissions from household combustion of家庭燃烧的煤,室内排放 201233 Coal-tar distillation 煤焦油蒸馏 201234 Coal-tar pitch 煤焦油沥青

6、201235 Coke production 焦炭制造 201236 Cyclophosphamide 环磷酰胺 201237 Cyclosporine 环孢霉素 201238 1,2-Dichloropropane 1,2-二氯丙烷 201639 Diethylstilbestrol 己烯雌酚 201240 Engine exhaust, diesel 发动机排放、柴油 201341 Epstein-Barr virus 巴尔病毒 201242 Erionite 毛沸石 201243Estrogen therapy, postmenopausal雌激素治疗绝经后 201244Estrogen

7、-progestogen menopausal therapy (combined)雌激素-孕激素更年期治疗 (联合) 201245 Estrogen-progestogen oral 雌激素-孕激素口服避孕药 (组合) 2012contraceptives (combined)46 Ethanol in alcoholic beverages 酒精饮料中的乙醇 201247 Ethylene oxide 环氧乙烷 201248 Etoposide 依托泊苷 201249Etoposide in combination with cisplatin and bleomycin依托泊苷结合顺铂和

8、博来霉素 201250Fission products, including strontium-90裂变产物,包括锶- 90 201251Fluoro-edenite fibrous amphibole氟代-浅闪石纤维角闪石 201752 Formaldehyde 甲醛,福尔马林 201253Haematite mining (underground)赤铁矿矿业(地下) 201254Helicobacter pylori (infection with)幽门螺杆菌(感染) 201255Hepatitis B virus (chronic infection with)乙型肝炎病毒(慢性感染)

9、 201256Hepatitis C virus (chronic infection with)丙型肝炎病毒(慢性感染) 201257Human immunodeficiency virus type 1 (infection with)人类免疫缺陷病毒 I 型(感染) 201258 Human papillomavirus types 人类乳头瘤病毒类型 201216, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 5916,18,31,33,35,39,45,51,52,56,58,5959Human T-cell lymphotropic virus

10、type I人类 T 淋巴细胞病毒 I 型 201260 Ionizing radiation (all types) 电离辐射(所有类型 ) 201261Iron and steel founding (occupational exposure during)钢铁铸造(职业暴露 ) 201262Isopropyl alcohol manufacture using strong acids使用强酸生产异丙醇 201263 Kaposi sarcoma herpesvirus 卡波济肉瘤疱疹病毒 201264 Leather dust 皮革尘埃 201265 Magenta producti

11、on 品红制造 201266 Melphalan 美法仑 201267Methoxsalen (8-methoxypsoralen) plus ultraviolet A radiation甲氧沙林甲氧补骨脂素花椒毒素+紫外线辐射201268 Methyl-CCNU 甲基环已亚硝脲 2012694,4-Methylenebis(2-chloroaniline) (MOCA)4,4-亚甲基(2-氯苯胺) 201270Mineral oils, untreated or mildly treated矿物油,未经处理或温和治疗 201271 MOPP and other combined MOPP（

12、氮芥、长春新碱、甲基苄肼、强的 2012chemotherapy including alkylating agents松）和其他联合化疗包括烷化剂72 2-Naphthylamine 2-萘胺 201273 Neutron radiation 中子辐射 201274 Nickel compounds 镍化合物 201275N-Nitrosonornicotine (NNN) and 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK)亚硝基降烟碱，亚硝胺 201276Opisthorchis viverrini(infection w

13、ith)泰国肝吸虫（麝猫后睾吸虫、香猫肝吸虫）(感染) 201277 Outdoor air pollution 室外空气污染 201678Outdoor air pollution, particulate matter in室外空气污染,颗粒物 201679Painter (occupational exposure as a)画家(职业暴露 ) 2012803,4,5,3,4-Pentachlorobiphenyl (PCB-126)多氯联苯 2012812,3,4,7,8-Pentachlorodibenzofuran多氯二苯并呋喃 201282 Phenacetin 非那西汀 201

14、283 Phenacetin, analgesic mixtures 非那西汀,包含止痛剂混合物 2012containing84 Phosphorus-32, as phosphate 磷-32，磷酸 201285 Plutonium 钚 201286 Polychlorinated biphenyls 多氯联苯 201687Polychlorinated biphenyls, dioxin-like, with a Toxicity Equivalency Factor (TEF) according to WHO (PCBs 77, 81, 105, 114, 118, 123, 126

15、, 156, 157, 167, 169, 189)类二恶英多氯联苯,毒性等价系数(TEF) 取自WHO(多氯联苯77,77,81,77,81,123,126,156,157,167,169,189)201688Radioiodines, including iodine-131放射性碘,包括碘- 131 201289Radionuclides, alpha-particle-emitting, internally deposited放射性核素, 粒子放射,内部沉积 201290Radionuclides, beta-particle-emitting, internally deposit

16、ed放射性核素, 粒子放射,内部沉积 201291Radium-224 and its decay products镭- 224 及其衰变产物 201292Radium-226 and its decay products镭- 226 及其衰变产物 201293Radium-228 and its decay products镭- 228 及其衰变产物 201294Radon-222 and its decay products氡- 222 及其衰变产物 201295 Rubber manufacturing industry 橡胶制造业 201296 Salted fish, Chinese

17、-style 中国式咸鱼 201297Semustine 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea, Methyl-CCNU司莫司丁(甲基环己亚硝脲) 201298 Shale oils 页岩油 201299Silica dust, crystalline, in the form of quartz or cristobalite二氧化硅粉尘、水晶、石英、方石英的形式 2012100Solar radiation 太阳辐射 2012101Soot (as found in occupational exposure of c

18、himney sweeps)烟尘(发现于烟囱清洁工的职业暴露) 2012102Sulfur mustard 硫芥 2012103Tamoxifen 它莫西芬 20121042,3,7,8-Tetrachlorodibenzo-para-dioxin四氯双苯环二噁英(TCDD) 2012105Thiotepa 三胺硫磷 2012106Thorium-232 and its decay products钍- 232 及其衰变产物 2012107Tobacco smoke, second-hand 吸二手烟 2012108Tobacco smoking 吸烟 2012109Tobacco, smok

19、eless 无烟烟草 2012110ortho-Toluidine 邻甲苯胺 2012111Treosulfan 苏消安曲奥舒凡 2012112Trichloroethylene 三氯乙烯 2014113Ultraviolet-emitting tanning devices紫外线放射日光浴设备 2012114Vinyl chloride 氯乙烯 2012115Wood dust 木粉 2012116X- and Gamma-Radiation X、 辐射 20122 类致癌物清单（共 357 种，含 2A 类 71 种， 2B 类 286 种）2A 类致癌物：对人类致癌性证据有限，对实验动物

20、致癌性证据充分。2B 类致癌物：对人类致癌性证据有限，对实验动物致癌性证据并不充分；或对人类致癌性证据不足，对实验动物致癌性证据充分。 序号 英文名称 中文名称确定时间（年） 亚类11-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)1-（2-氯乙基）-3-环己基 -1-亚硝基脲（CCNU ）1987 2A2 1,2,3-Trichloropropane 1,2,3-三氯丙烷 1995 2A3 1,2-Dimethylhydrazine 1,2-二甲基肼 1999 2A4 1,3-Propane sultone 1,3-丙烷磺内酯 2017 2

21、A5 1-Nitropyrene 1-硝基芘 2014 2A6 2-Nitrotoluene 2-硝基甲苯 2013 2A7 4-Chloro-ortho-toluidine 4-氯-邻-甲苯胺 2010 2A8 5-Methoxypsoralen 5-甲氧基补骨脂素 1987 2A9 6-Nitrochrysene 6-硝基屈,6- 硝基联苯 2014 2A10 Acrylamide 丙烯酰胺 1994 2A11 Adriamycin 阿霉素 1987 2A12alpha-Chlorinated toluenes (benzal chloride, benzotrichloride, benzyl chloride) and benzoyl chloride (combined -氯代甲苯（二氯甲基苯,三氯甲苯,氯化苄）和苯甲酰氯(混合暴露)1999 2A