Chen Dapeng MD, PhDPediatric Department West China Second University HospitalTo understand the characteristics of neonatal bilirubin metabolism.ObjectiveJaundice(黄疸 )Term baby (37w) 50%Incidence in NewbornPreterm baby(37w) 80%Core of Bilirubin MetabolismUnconjugated bilirubin(未结合胆红素 )Conjugated bilirubin(结合胆红素)glucuronic acid (葡萄糖醛酸)Metabolism of Bilirubin Metabolism of Bilirubin Red Blood Cell1. Increase of bilirubin productionAdult 3.8mg/L Newborn 8.5mg/LRBC life span120 d 80 dRBC Quantity4.5x1012/L 6.5x1012/L