陈培亮-中央大学物理系-国立中央大学.ppt

1、Overview of research in Biophysics Institute NCU. 中央大學生物物理所From DNA to collective behavior of organisms,http:/www.phy.ncu.edu.tw/ibp/,Soft Condensed Matter,Biophysics,Institute of BioPhysics at NCU中央大學生物物理所,Physics Dept.,Center for Complex Systems複雜系統中心,Brain Research Center,UST聯合大學腦科學中心,Life Scienc

2、e生命科學系,Institute of Phys., Academia Sinica中研院物理所,Inst. Systems Biology & Bioinformatics系統生物所,Why BioPhysics ?,Material Nature of Bio-substances affect Biological properties. (Evolution made use of the physical properties of bio-materials)Physical principles & Laws holds from microscopic level macros

3、copic levelTraditional Biology is descriptive, non-quantitative,Why BioPhysics ?,Physics is universal. Rise of molecular biology: DNA, RNA, protein are universal in all living mattersUniversality in Central Dogma: DNARNAproteinBiological functionsNew, interesting, exciting & useful.Lots of unsolved

4、important problems.Techniques & Methodology in physics can probe the fundamental principles in bio-systems of a wide spectrum of scales in a quantitative way.,國立中央大學 生物物理研究所,Officially established in 2004教授: 6 副教授: 1 助理教授 3合聘教授: 2 合聘助理教授: 1現有從事生物物理領域在學研究生 碩士班：23 博士班：8 博士後: 3 以物理之技術或方法去探討生物系統中存在之基本原理

5、，從而對生物過程提供深入及定量之了解。5年500億頂尖中心經費建立生物物理共用核心設施 歡迎物理與非物理背景同學加入.中大及中研院提供獎學金,BioPhysics Institute NCU,Officially established in 2004Professors: 6 Assoc. Prof.: 1 Assist. Prof. 3Adj. Prof.: 2 Adj. assist.prof.: 1Graduate students working on areas in biophysics M.S.：23 Ph. D.：8 Postdocs: 5aims at achieving

6、some quantitative description of biological processes and search for the fundamental principles buried in these highly complex biological phenomena5 years 500Bgrant to support research & building of core facility labs.Cross-disciplinary: researchers/students from physics & non-physics background,Wid

7、e Spectrum,Length Scales:nm mm mm cm m kmDNA,RNA,protein, intracellular, virus, bacteria, Intercellular, collective motion, insects, animanls/plants, migrationTime Scales: fs ps ms ms s e transfer,H-bonding,water DNA,RNA,protein rearrangement , protein folding DNA transcription hr day year Byr cell

8、division Earth organisms , animal migration evolutionKnowledge: Interdisciplinary 跨越各學科領域 MathematicsPhysicsChemistryBiologyMedicalBiophysicist is a TRUE Scientist !需要物理與非物理背景人材加入!,BioPhysics Theory Groups at NCU,陳培亮 Peilong Chen: bio-hydrodynamics, mechanics of propulsion in living organisms, patte

9、rn formation in biology陳宣毅 Hsuen-Yi Chen: complex fluids, cell adhesion, collective motion in flocks黎璧賢 Pik-Yin Lai: DNA physics, biomolecular chain models, neurons, biological networks 李紀倫 Chi-Lun Lee: protein folding, charged biomolecules梁鈞泰 Kwan-tai Leung: self-propelling motion in organisms, flo

10、cking, non-equilibrium bio-processes高仲明 Chung-ming Ko: Evolution models, astrobiology王敏生 Min-Sheng Wang: Neural Networks, brain wave & MEG analysis李弘謙 Hoong-Chien Lee: Bioinformatics, protein physics, genome/DNA sequence analysis,Soft matters,Biophysics,BioPhysics Experimental Labs at NCU,Complex Sy

11、stem Lab.伊林 Lin I: micro-motion of bio- and soft materials in confined spots, dynamics of neuronal system, laser pulse-soft matter interaction,Biophysics Lab.陳方玉 Fang Yu Chen: Biomembrane, Membrane-active Peptides, Effect of peptide-forming pore on neuron function,Soft-condensed Matter Lab.陳培亮 Peilo

12、ng Chen: bio-hydrodynamics, mechanics of propulsion in living organisms,Bio-Soft Matters Lab.黎璧賢 Pik-Yin Lai, 陳志強 C.K. Chan & 林耿慧 K.H.Lin: interactions in cells, neuronal networks, DNA mechanics & hydrodynamics, biomaterials,Bio-Soft Core Facilities Lab. : BioAFM, Confocal microscopy, Wet Labs, Bio samples, fast imaging systems, fluorescence microscopy,Bio-membrane Lab.薛雅薇 Ya-Wei Hsueh: lipid rafts in cell membranes, NMR spectroscopy, AFM measurement,