随机对照设计在近视防治有效性研究中的应用.ppt

1、Eye exercises for Myopia,LIANG YuanboEye Hospital of Wenzhou Medical University,Myopia prevalence in urban and rural Chinese children,GZ: 78.4%, -1.50D,SY F: 55.0%, -0.84D,SY M: 36.7%, -0.23D,YX: 43.0%, -0.50D,Zhao (2000), AJO; He (2004), IOVS; He (2007), Ophthalmology; Liang YB: unpublished data: H

2、andan offspring study,2,HOMS: 55.6%, -1.51D,Beijing eye Study 2001: Urban adult (40 years): Handan Eye Study2006: Rural adult (40 years):,Xu (2005), Ophthalmology; Liang (2009), Ophthalmology,Prevalence of Myopia in urban and rural Chinese adults,3,18.8%,21.8%,Prevalence of myopia by year of birth i

3、n the Handan Eye Study 2006,%,Pro-myopia factors,Con-myopia factors,-1D,Tug of war ： after 1970s,+1D,？,Handan Offspring Eye Study (HOMS 2010),Beijing Myopia Progression Study (BMPS 2010),Methods Aged 6-17 Same procedures for data collection Visual acuityOcular biometryQuestionnairesObtained all chil

4、drens cycloplegic refraction and parental non-cylcoplegic refraction,7,DefinitionsChildrens refractive error: average of the cycloplegic spherical equivalent (SE, sphere+1/2 cylinder) of both eyesParental refractive error: average of non-cycloplegic SE of father and mother (4 eyes)Refractive error d

5、ifference between parents and their children = parental SE - childrens SEGenerational shift towards myopia: estimated refractive error difference at the age of 18 90% myopia stabilization at: 18 yrs 15.182.47Myopia: SE -0.50D; emmetropia: -0.50 SE 35岁者妊娠期糖尿病的患病率是25岁者的2.06倍Prevalence of DM in China，

6、1979 0.67%， 2.5%， 3.2%， 2010 9.7%,Figure 3. Results of network meta-analysis using single vision spectacle lenses/placebo as referent intervention. Atr atropine; Atr H high-dose atropine(1% or 0.5%); Atr L low-dose atropine (0.01%); Atr M moderate-dose atropine (0.1%); BSLs bifocal spectacle lenses;

7、 CrI credible interval; Cyc cyclopentolate; MOA more outdoor activities (14e15 hrs/wk); OK orthokeratology; PASLs progressive addition spectacle lenses; PBO placebo;PBSLs prismatic bifocal spectacle lenses; PDMCLs peripheral defocus modifying contact lenses; PDMSLs peripheral defocus modifying spect

8、aclelenses; Pir pirenzepine; RGPCLs rigid gas-permeable contact lenses SCLs soft contact lenses; SVSLs single vision spectacle lenses; Tim timolol;USVSLs undercorrected single vision spectacle lenses.,What we can do for myopia prevention and control?,Chinese traditional medicine can contribute? Acup

9、unctureMeihua ZhenEr zhenEye exercises,The history of eye exercises practice in China,Beijing, 1960s1972, MOE：twice daily, eye exercise 2008，New version of eye exercises,Researches on eye exercise and myopia,国际期刊发表的眼保健操论文,Childrens spherical equivalent (SE) and odds ratio (OR) for myopia for each it

10、em of the eye exercises of acupoints questionnaire,Lin Z, Gao TY, Jhanji V, et al. BMC Complement Altern Med, 2016, accepted.,Childrens convergence insufficiency symptom survey scores(CISS) and coefficientsforeach item ofthe eye exercises of acupoints questionnaire,Conclusions,There is no evidence to show eye exercises is effective in preventing myopia onset or progression Difficulties in research design:Governmental mandatory practice Control group is not allowedInternational school,谢 谢！,