痛风与高尿酸血症Gout and Hyperuricemia,J. Gillray, 1799.,历史回顾 流行病学 生化机制与病理生理学 高尿酸血症 并发症: 痛风 肾脏病变 治疗,痛风一种古老的疾病,2500 B.C.:埃及木乃伊发现足部痛风石,1500 B. C.,痛风:最早的描述和化石,西医之父希波克拉底,全面的临床描述,认为是体内“体液”流淌在下肢的结果 “The unwalkable disease” Podagra Gonagra As a “disorder of the rich” association with dietary excess and intemperate lifestye,“A women does not take the gout, unless her menses be stoped.” “A youth does not get gout before sexual intercourse.”,希波克拉底关于痛风的名言:,最早描述了痛风石,公元三世纪广泛使用 To referred to the Hippocratic notion o