1、Enteric Diseases of Young Pigs仔猪肠道疾病作者： Larry Firkins, DVM, MS, MBACollege of Veterinary MedicineUniversity of Illinois美国伊利诺斯大兽医学院Diarrhea remains one of the leading causes of neonatal mortality in swine下痢一直是新生仔猪死亡的主要原因下痢一直是新生仔猪死亡的主要原因Definition of Diarrhea下痢的定义n Excess water in feces relative to dr
2、y matter.粪中含水量过大n Normally, much of the fluid is absorbed in the small intestine before it exits the ileum 通常，大部分水都在进入回肠之间就在小肠中被吸收了n Colon serves to conserve water and electrolytes结肠只起吸收水和电解质的作用Mechanisms of Diarrhea下痢的机理n Secretory Diarrhea分泌性下痢n Result of the effect of enterotoxins secreted by bac
3、teria and some viruses细菌和其它病毒分泌的肠毒素造成的结果n Alteration in secretion of electrolytes, water, and bicarbonate: gradient pulls water into lumen电解质、水和碳酸氢钠的分泌发生改变：使水进入肠腔n Absorption continues: Chyle in lymphaticsMechanisms of Diarrhea下痢的机理n Malabsorptive Diarrhea吸收不良性下痢n Reduction in surface area of intest
4、ine肠粘膜表面积减少n Loss of absorptive capacity吸收能力减弱n Villous atrophy绒毛萎缩n Chyle absent in lymphatics淋巴乳糜缺乏n Undigested ingesta ferments未消化的食糜发酵Mechanisms of Diarrhea下痢的机理n Effusive Diarrhea渗漏性下痢n Result of severe damage to mucosa粘膜严重受损的结果n Necrotoxins produced by bacteria细菌产生的坏死毒素n Leakage of serum prote
5、ins and water due to vascular damage血管受损导致血清蛋白质和水漏出n Loss of absorptive capacity吸收能力减弱Arriving at a Diagnosis诊断n History病史n Age of onset发病年龄n Vaccination history免疫接种历史n Sudden death vs. protracted diarrhea猝死和长期下痢Arriving at a Diagnosis诊断n Selection of specimens病料采集n Diarrhea of 24 hrs or less下痢开始后 24小时以内n Untreated未经治疗n Avoid pigs which “died during the night”不要从夜间死亡的猪采集病料
