1、Background Hypertension is a global public health problem of major magnitude An estimated 30-40% of the adult population in the developed world suffers from this condition. Despite numerous safe and effective pharmacological therapies, only50% of patients achieve blood pressure control to guideline
2、targets Renal sympathetic efferent and afferent nerves, which lie in the wall of the renal artery, have been recognized as seminal in the initiation and maintenance of systemic hypertensionCatheter-based renal sympathetic denervation for resistant hypertension:a multicentre safety and proof-of-principle cohort study. Lancet 2009; 373: 1275