肝内胆汁淤积的诊断步骤与治疗要点慢性肝病伴肝内胆汁淤积（IHC)发生率M.Bartolini,IP.Almasio,et,al.MulticentreSurveyofthePrevalenceofIntrahepaticCholestasisin2520ConsecutivePatientswithNewlyDiagnosedChronicLiverDisease.DrugInvestigation4(Suppl.4):83-89,1992胆汁淤积发生机制BA健康志愿者(nmol/L)胆汁淤积患者(nmol/L)CDCA257568460TCDCA12022165784370GCDCA776112285355734CA18283173137TCA180475448713419GCA233565622215714UDCA138252011TUDCA517522 未妊娠妇女妊娠妇女正常胆汁淤积(n=20)(n=38)(n=39)总胆汁酸(mol/L)5.70.46.60.362.18.2胆酸的比率甘氨酸/牛磺酸1.60.21.40.10.80.1初级胆酸/次级胆酸1.80.12.00.17
