胰岛素强化治疗的临床应用胰岛素强化治疗的临床应用 马建马建华华 吴锦丹吴锦丹MIMicrovascular endpoints80 Adjusted Incidence per1000 Person-Years(%)Updated Mean A1C(%)60 40 20 0 5 6 7 8 91011Adapted from Stratton IM et al.BMJ.2000;321:405-412.UKPDS:Cardiovascular Risk Increases With Increasing Glyceamia达到并保持HbA1c达标FPG和PPG的作用贡献%A1C范围(%)30%40%45%50%70%空腹血糖(FPG)70%60%55%50%30%02040608010010.210.2-9.39.2-8.58.4-7.37.3餐后血糖(PPG)Monnier L,et al,Diabetes Care.2003 Mar;26(3):881-5 全新的2型糖尿病胰岛素治疗理念一天中的时间点血糖(mg/dl)正常人40030020010006:0010:0014:0018