哮喘炎症的非创伤性检测哮喘炎症的非创伤性检测 指标指标及临床意义及临床意义苏州大学附属儿童医院 郝创利Airways Narrowing哮哮 喘喘 的的 病病 理理Trigger factorMucus pluggingAirway wall oedemaSmooth muscle spasm确定是否有气道阻塞确定是否有气道阻塞:用肺功能仪用肺功能仪Sensitivity=35%Smith et al.AJRCCM.,2004litresFEV1seconds1 2 3 4 5 6 NORMALOBSTRUCTEDGINA 哮喘的定义哮喘的定义 chronic inflammatory disorder of the airways increase in airway hyper-responsiveness recurrent episodes of respiratory symptoms variable airflow obstruction reversible spontaneously or with treatment.Global INitiative for As