系统性红斑狼疮系统性红斑狼疮(SLE)SystemicLupusErythematosus SystemicLupusErythematosus ManyManyDifferent Different Auto-Auto-antibodiesantibodiesMultipleMultipleSystem System InvolvementInvolvementSLEonsetbysexandageEtiologyandpathogenesispathologyClinicalfindingsLaboratoryfindingsDiagnosisTreatmentprognosisEtiologygeneticfactorsenvironmentalfactorsSexhormonalfactors PathogenesisExcessive,abnormal production of“self”antibodies and formation of IC.Autoantibodies against nuclear,cytoplasmic and membrane compone