股骨头无菌性坏死股骨头无菌性坏死Osteonecrosis of the Femoral HeadOsteonecrosis of the Femoral Head股骨头坏死Osteonecrosis of the Femoral Head概述概述病因病因病理病理诊断断治治疗2 2First described by Munro in 1738.In 1835 Curveilhier depicted femoral head morphological changes secondary to interruption of blood flow.First large sample size report by Mankin in 1962.3 34 4骨坏死是指骨的血供中断后骨骨坏死是指骨的血供中断后骨细胞和胞和骨髓成分死亡及随后的修复骨髓成分死亡及随后的修复股骨股骨头坏死是一种由于骨坏死是一种由于骨细胞死亡,胞死亡,继 而(可能)而(可能)导致股骨致股骨头结构改构改变引引起塌陷(疼痛)和功能障碍的疾病起塌陷(疼痛)和功能障碍的疾病概 述 发病发病 年轻患者(年轻患者(年轻患者(