Ag-Ab reation:ELISA,Immunohistochemistry,FACS,Westernblot,Hybridoma&monoclonalantibodyCell function:proliferation3HTdRMTTCFSECytotoxicity51CrAnimal experiment非共价键结合I.Antigen-Antibody Reaction 抗体的互补决定区抗体的互补决定区(CDRs)抗原决定簇抗原决定簇(antigenic determinant)又称表位又称表位(epitope)非共价键结合非共价键结合CDR1CDR2CDR3CDR1CDR2CDR3CDR:Complementarity Determining RegionFR:Framework Region FR1CDR1FR2CDR2FR3CDR3FR4HLComplementarity-determining regions(CDRs):Antigenic DeterminantSpecificity 特异性 Features of Ag-Ab Reaction Reversibil