Cytokine Cytokines Cytokines are are small small secreted secreted proteinsproteins which which mediate mediate and and regulate regulate immunity,immunity,inflammation,inflammation,and and hematopoiesis.hematopoiesis.They They are are produced produced de de novonovo in in response response to to an an immune immune stimulus.stimulus.Cytokines Cytokines regulate regulate the the intensity intensity and and duration duration of of the the immune immune responseresponse by by stimulating stimulat