背景l颅脑外伤治疗现状颅脑外伤治疗现状l2007版颅脑外伤救治指南版颅脑外伤救治指南(3ed.)1 颅脑外伤后颅脑外伤后7天之前,天之前,PN/EN:A 未瘫痪病人:未瘫痪病人:140%BEE B 瘫痪病人:瘫痪病人:100%BEE 2 蛋白质占热卡大于蛋白质占热卡大于15%3 在在72小时前开始营养支持小时前开始营养支持背景l营养支持的地位营养支持的地位:为什么需营养支持为什么需营养支持?l时机时机?l途径途径?l制剂制剂?l允许性低热卡营养允许性低热卡营养,过度喂养过度喂养?lTGC?Metabolic consequences of head injury Metabolic consequences of head injury(From Young and Ott with permission)(From Young and Ott with permission)Head injury (Central injury)Cytokines Hormones Prostaglandins Others (Systemic injury)Acute phase response