1、第八章 生物碱类药物分析 Chapter 8 The Analysis of Alkaloids 药物分析课件系列Specialidentification testAssayAlkaloidsProperty Impuritytest Classification contents fundamental requirements reviewContents 1. The structures and properties of Alkaloids(6 groups);2. The primary identification tests of Alkaloids;3. Special i
2、mpurity tests for the Alkaloids;4. Assays of Alkaloids.Fundamental requirements 1. Mastering the theories, procedures and conditions: non-aqueous titration, extractive titration, and acid dye colorimetry; 2. Understanding the structures and properties of Alkaloids;3. Understanding the specific impur
3、ity tests of Alkaloids;4. Understanding the applications of high performance liquid chromatographic and gas chromatographic methods in assays of Alkaloids. 5. Familiarizing with the primary identification tests of Alkaloids;Fundamental requirements Benzoalkylamines TropanesQuinolines IsoquinolinesIn
4、doles Xanthinesv Classification Press here to seethe detailed classificationGo to reviewephedrine hydrochloride pseudoephedrine hydrochloride colchicin The structural characteristic of this type alkaloids is that the N atom is in the alphatic chain rather than in aromatic ring. The typical drugs are
5、 Ephedrine hydrochloride, Pseudoephedrine hydrochloride, Colchicin. Benzoalkylamineatropine sulfate anisodamine hydrobromide Tropanes This type of alkaloids are the condensation products of alkaloid derived from tropanes and different kinds of esters. The typical drugs are atropine and anisodamine.Quinolinesquinine sulfate quinidine sulfate The commonly used drugs are quinine sulfate, quinidine sulfate etc. Isoquinolines morphine hydrochloride codeine phosphate The typical drugs are morphine, codeine, narcotine.
