1、2016 年学院科研与教学研究成果统计表一、SCI 论文（201 篇）1. Cao, Ye; Guan, Kai; He, Xiang; Wei, Congwen; Zheng, Zirui; Zhang, Yanhong; Ma, Shengli; Zhong, Hui; Shi, Wei. Yersinia YopJ negatively regulates IRF3-mediated antibacterial response through disruption of STING-mediated cytosolic DNA signaling. BIOCHIMICA ET BIOP
2、HYSICA ACTA-MOLECULAR CELL RESEARCH, 2016, 1863:3148-3159.2.Wei, Ying; Lu, Jun; Lu, Tong; Meng, Feihong; Xu, Jia; Wang, Li; Li, Yang; Wang, Liping; Li, Fei. Formation of lamellar micelle-like oligomers and membrane disruption revealed by the study of short peptide hIAPP(18-27). PHYSICAL CHEMISTRY CH
3、EMICAL PHYSICS, 2016, 18:29847-29857.3. Shen, Zhenwei; Bowen, Richard A.; Ge, Peng; Yu, Jinfei; Shen, Yanjie; Kong, Wei; Jiang, Chunlai; Wu, Jinchang; Zhu, Changlin; Xu, Yanjun; Wei, Wei; Rudenko, Larisa; Kiseeva, Irina; Xu, Fei. Evaluation of a candidate live attenuated influenza vaccine prepared i
4、n Changchun BCHT (China) for safety and efficacy in ferrets. VACCINE, 2016, 34:5953-5958.4. Zhang Yong; Cui Lili; Li Feng; Shi Nianqiu; Li Chunlei; Yu Xianghui; Chen Yan; Kong Wei. Design, fabrication and biomedical applications of zein-based nano/micro-carrier systems. INTERNATIONAL JOURNAL OF PHAR
5、MACEUTICS, 2016, 513:191-210.5. Li, Peng; Zhang, Ming; Sun, Xueke; Guan, Shuwen; Zhang, Guang; Baumgarten, Martin; Muellen, Klaus. A dendrimer-based highly sensitive and selective fluorescence quenching sensor for Fe3+ both in solution and as film. BIOSENSORS Brooks, Angela N.; Fan, Jean; Wan, Youzh
6、ong; Gambe, Rutendo; Li, Shuqiang; Hergert, Sarah; Yin, Shanye; Freeman, Samuel S.; Levin, Joshua Z.; Fan, Lin; Seiler, Michael; Buonamici, Silvia; Smith, Peter G.; Chau, Kevin F.; Cibulskis, Carrie L.; Zhang, Wandi; Rassenti, Laura Z.; Ghia, Emanuela M.; Kipps, Thomas J.; Fernandes, Stacey; Bloch,
7、Donald B.; Kotliar, Dylan; Landau, Dan A.; Shukla, Sachet A.; Aster, Jon C.; Reed, Robin; DeLuca, David S.; Brown, Jennifer R.; Neuberg, Donna; Getz, Gad; Livak, Kenneth J.; Meyerson, Matthew M.; Kharchenko, Peter V.; Wu, Catherine J. Transcriptomic Characterization of SF3B1 Mutation Reveals Its Ple
8、iotropic Effects in Chronic Lymphocytic Leukemia. CANCER CELL, 2016, 30:750-763.7. Wu, Di; Wang, Chenhui; Yang, Jiebing; Wang, Hao; Han, Haobo; Zhang, Aijun; Yang, Yan; Li, Quanshun. Improving the Intracellular Drug Concentration in Lung Cancer Treatment through the Codelivery of Doxorubicin and miR
9、-519c Mediated by Porous PLGA Microparticle. MOLECULAR PHARMACEUTICS, 2016, 13:3925-3933.8. Yang, Zizhao; Li, Li; Hu, Haihong; Xu, Mingcheng; Gu, Jingkai; Wang, Zaijie Jim; Yu, Lushan; Zeng, Su. Reverse of Acute and Chronic Morphine Tolerance by Lithocholic Acid via Down-Regulating UGT2B7. FRONTIERS
10、 IN PHARMACOLOGY, 2016, 7:4049. Cao, Hao; Yang, Xue; Jin, Lanna; Han, Weiwei; Zhang, Yingjiu. Module recombination and functional integration of oligosaccharide-producing multifunctional amylase. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2016, 133:196-202.10. Wang, Dejiang; Di, Xiangjun; Fu, Lu; L
11、i, Yingnan; Han, Xiao; Wu, Hui; Cai, Linjun; Meng, Xiangyu; Jiang, Chunlai; Kong, Wei; Su, Weiheng. Analysis of serum -amyloid peptides, 2-macroglobulin, complement factor H, and clusterin levels in APP/PS1 transgenic mice during progression of Alzheimers disease. NEUROREPORT, 2016, 27:1114-1119.11.
12、 Zhai, Jing-hui; Wu, Yi; Wang, Xiao-ying; Cao, Yue; Xu, Kan; Xu, Li; Guo, Yi. Antioxidation of Cerium Oxide Nanoparticles to Several Series of Oxidative Damage Related to Type II Diabetes Mellitus In Vitro. MEDICAL SCIENCE MONITOR, 2016, 22:3792-3797.12. Li, Yuhuan; Lee, Robert J.; Yu, Kongtong; Bi,
13、 Ye; Qi, Yuhang; Sun, Yating; Li, Yujing; Xie, Jing; Teng, Lesheng. Delivery of siRNA Using Lipid Nanoparticles Modified with Cell Penetrating Peptide. ACS APPLIED MATERIALS Wang, Lebing; Wang, Shuxia; Xiao, Tiqiao; Chen, Min; Shao, Qun; York, Peter; Singh, Vikaramjeet; Yin, Xianzhen; Gu, Jingkai; Z
14、hang, Jiwen. Three dimensional structural insight of laser drilled orifices in osmotic pump tablets. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2016, 93:287-294.14. Li, Mengzhen; Li, Yue; Sasaki, Shin-ichi; Song, Jiaxing; Wang, Chen; Tamiaki, Hitoshi; Tian, Wenjing; Chen, Gang; Miyasaka, Tsutomu;
15、Wang, Xiao-Feng. Dopant-Free Zinc Chlorophyll Aggregates as an Efficient Biocompatible Hole Transporter for Perovskite Solar Cells. CHEMSUSCHEM, 2016, 9:2862-2869.15. Long, Shiyang; Tian, Pu. Nonlinear backbone torsional pair correlations in proteins. SCIENTIFIC REPORTS, 2016, 6:3448116. Sun, Heping
16、; Wang, Jiang; Sun, Yantong; Peng, Wenwen; Sun, Lingxia; Yang, Yan; Gu, Jingkai. Rapid and sensitive liquid chromatography with tandem mass spectrometry method for the simultaneous quantification of yonkenafil and its major metabolites in rat plasma. JOURNAL OF SEPARATION SCIENCE, 2016, 39:3700-3708
17、.17. Jia, Dongxu; Lu, Wenqian; Zhang, Xinrui; Cai, Guangsheng; Teng, Lirong; Wang, Xinyu; Zhang, Minghai; Zeng, Yan; Liang, Chunhua; Wang, Di. Calf Spleen Extractive Injection (CSEI), a small peptides enriched extraction, induces human hepatocellular carcinoma cell apoptosis via ROS/MAPKs dependent
18、mitochondrial pathway. JOURNAL OF PHARMACOLOGICAL SCIENCES, 2016, 132:122-130.18. Liu Rui; Wang Yan; Ma Yudan; Wu Yi; Guo Yi; Xu Li. Effects of the Molecular Weight of PLGA on Degradation and Drug Release In vitro from an mPEG-PLGA Nanocarrier. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2016, 32:848
19、-853.19. Qian, Mengdan; Shan, Yaming; Guan, Shanshan; Zhang, Hao; Wang, Song; Han, Weiwei. Structural Basis of Fullerene Derivatives as Novel Potent Inhibitors of Protein Tyrosine Phosphatase 1B: Insight into the Inhibitory Mechanism through Molecular Modeling Studies. JOURNAL OF CHEMICAL INFORMATIO
20、N AND MODELING, 2016, 56:2024-2034.20. Wang, Wei; Tan, Junjie; Xing, Yuhua; Kan, Naipeng; Ling, Jingyi; Dong, Guifu; Liu, Gang; Chen, Huipeng. p43 induces IP-10 expression through the JAK-STAT signaling pathway in HMEC-1 cells. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2016, 38:1217-1224.21. Su,
21、Jiaming; Sui, Yi; Ding, Jian; Li, Fuqiang; Shen, Shuang; Yang, Yang; Lu, Zeming; Wang, Fei; Cao, Lingling; Liu, Xiaoxia; Jin, Jingji; Cai, Yong. Human INO80/YY1 chromatin remodeling complex transcriptionally regulates the BRCA2-and CDKN1A-interacting protein (BCCIP) in cells. PROTEIN Yang, Jiebing;
22、Xing, Zhen; Han, Haobo; Wang, Tingting; Zhang, Aijun; Yang, Yan; Li, Quanshun. Phenylboronic acid-functionalized polyamidoamine-mediated Bcl-2 siRNA delivery for inhibiting the cell proliferation. COLLOIDS AND SURFACES B-BIOINTERFACES, 2016, 146:318-325.23. Xi, Hualong; Yuan, Ruosen; Chen, Xiaoxu; G
23、u, Tiejun; Cheng, Yue; Li, Zhuang; Jiang, Chunlai; Kong, Wei; Wu, Yongge. Purification and on-column refolding of a single-chain antibody fragment against rabies virus glycoprotein expressed in Escherichia coli. PROTEIN EXPRESSION AND PURIFICATION, 2016, 126:26-32.24. He, Hongming; Han, Haobo; Shi,
24、Hui; Tian, Yuyang; Sun, Fuxing; Song, Yang; Li, Quanshun; Zhu, Guangshan. Construction of Thermophilic Lipase-Embedded Metal Organic Frameworks via Biomimetic Mineralization: A Biocatalyst for Ester Hydrolysis and Kinetic Resolution. ACS APPLIED MATERIALS Zhang, Wei; Sun, Tingting; Gu, Jingkai; Xie,
25、 Zhigang; Jing, Xiabin. Effect of Molecular Structure on Stability of Organic Nanoparticles Formed by Bodipy Dimers. LANGMUIR, 2016, 32:9575-9581.26. Yang, Zi-Zhao; Li, Li; Wang, Lu; Xu, Ming-Cheng; An, Sai; Jiang, Chen; Gu, Jing-Kai; Wang, Zai-Jie Jim; Yu, Lu-Shan; Zeng, Su. siRNA capsulated brain-
26、targeted nanoparticles specifically knock down OATP2B1 in mice: a mechanism for acute morphine tolerance suppression. SCIENTIFIC REPORTS, 2016, 6:-.3333827. Bing, Wei; Sun, Hanjun; Yan, Zhengqing; Ren, Jinsong; Qu, Xiaogang. Programmed Bacteria Death Induced by Carbon Dots with Different Surface Cha
27、rge. SMALL, 2016, 12:4713-4718.28. Liao, Yi; Niu, Xiaojia; Chen, Bailing; Edwards, Holly; Xu, Liping; Xie, Chengzhi; Lin, Hai; Polin, Lisa; Taub, Jeffrey W.; Ge, Yubin; Qin, Zhihui. Synthesis and Antileukemic Activities of Piperlongumine and HDAC Inhibitor Hybrids against Acute Myeloid Leukemia Cell
28、s. JOURNAL OF MEDICINAL CHEMISTRY, 2016, 59:7974-7990.29. Li, Chunxiang; Dong, Yu; Liu, Minxuan; Lu, Ping; Li, Wenying; Wang, Yingnan; Cui, Xiyan; Zhou, Hui; Xu, Yue. Ancient DNA analysis of Panicum miliaceum (broomcorn millet) from a Bronze Age cemetery in Xinjiang, China. VEGETATION HISTORY AND AR
29、CHAEOBOTANY, 2016, 25:469-477.30. Li, Yang; Liu, Xiaokang; Jiang, Dan; Lin, Yingjia; Wang, Yushi; Li, Qing; Liu, Linlin; Jin, Ying-Hua. Betulin induces reactive oxygen species-dependent apoptosis in human gastric cancer SGC7901 cells. ARCHIVES OF PHARMACAL RESEARCH, 2016, 39:1257-1265.31. Niu, Xiaoj
30、ia; Zhao, Jianyun; Ma, Jun; Xie, Chengzhi; Edwards, Holly; Wang, Guan; Caldwell, J. Timothy; Xiang, Shengyan; Zhang, Xiaohong; Chu, Roland; Wang, Zhihong J.; Lin, Hai; Taub, Jeffrey W.; Ge, Yubin. Binding of Released Bim to Mcl-1 is a Mechanism of Intrinsic Resistance to ABT-199 which can be Overcom
31、e by Combination with Daunorubicin or Cytarabine in AML Cells. CLINICAL CANCER RESEARCH, 2016, 22:4440-4451.32. Liu, Mingyuan; Sun, Yantong; Zhao, Sen; Li, Youxin; Piao, Riyang; Yang, Yan; Gu, Jingkai. A novel prodrug strategy to improve the oral absorption of O-desmethylvenlafaxine. EXPERIMENTAL AN
32、D THERAPEUTIC MEDICINE, 2016, 12:1611-1617.33. Fu, Jie; Sun, Fengying; Liu, Wenhua; Liu, Yanfei; Gedam, Manasee; Hu, Qi; Fridley, Colleen; Quigley, Harry A.; Hanes, Justin; Pitha, Ian. Subconjunctival Delivery of Dorzolamide-Loaded Poly(ether-anhydride) Microparticles Produces Sustained Lowering of
33、Intraocular Pressure in Rabbits. MOLECULAR PHARMACEUTICS, 2016, 13:2987-2995.34. Wang, Di; Zhang, Yongfeng; Wang, Chunyue; Jia, Dongxu; Cai, Guangsheng; Lu, Jiahui; Wang, Di; Zhang, Zhang-Jin. 18 beta-Glycyrrhetinic Acid, a Novel Naturally Derived Agent, Suppresses Prolactin Hyperactivity and Reduce
34、s Antipsychotic-Induced Hyperprolactinemia in In Vitro and In Vivo Models. NEUROCHEMICAL RESEARCH, 2016, 41:2233-2242.35. Liu, Zhen; Ran, Xiang; Liu, Jianhua; Du, Yingda; Ren, Jinsong; Qu, Xiaogang. Non-toxic lead sulfide nanodots as efficient contrast agents for visualizing gastrointestinal tract.
35、BIOMATERIALS, 2016, 100:17-26.36. Xia, Qiu; Geng, Fei; Zhang, Fang-Fang; Liu, Chen-Lu; Xu, Ping; Lu, Zhen-Zhen; Zhang, Hai-Hong; Kong, Wei; Yu, Xiang-Hui. Enhancement of fibroblast activation protein alpha-based vaccines and adenovirus boost immunity by cyclophosphamide through inhibiting IL-10 expr
36、ession in 4T1 tumor bearing mice. VACCINE, 2016, 34:4526-4535.37. Turner, Tiffany; Shao, Qiujia; Wang, Weiran; Wang, Yudi; Wang, Chenliang; Kinlock, Ballington; Liu, Bindong. Differential Contributions of Ubiquitin-Modified APOBEC3G Lysine Residues to HIV-1 Vif-Induced Degradation. JOURNAL OF MOLECU
37、LAR BIOLOGY, 2016, 428:3529-3539.38. Xu, Qiu-Qiu; Hou, Qi-Lan; Liu, Wei; Wang, Hai-Jing; Liao, Wei-Wei. Copper-Promoted Cyclization of alpha-Amino Nitrile-Tethered Enynes: Controllable Synthesis of 3-Azabicyclo4.1.0hepta-2,4-dienes and 4,5-Dihydro-3H-azepines. ORGANIC LETTERS, 2016, 18:3854-3857.39.
38、 Ma Xiaoyuan; Wu Yi; Zhang Yanjing; Teng Lesheng; Xie Jing; Liao Weiwei. Regioselective Synthesis of Functionalized Dihydroquinolines via Organocatalytic Allylic Alkylation. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2016, 32:634-640.40. Zhao, Li; Zhang, Pupu; Long, Shiyang; Wang, Linlin; Jin, Hanyo
39、ng; Han, Weiwei; Tian, Pu. Investigating the substrate binding mechanism of sulfotransferase 2A1 based on substrate tunnel analysis: a molecular dynamics simulation study. JOURNAL OF MOLECULAR MODELING, 2016, 22:-.17641. Li, Xiaojiao; Liu, Chang; Wu, Min; Zhang, Hong; Sun, Yanfu; Cheng, Longmei; Che
40、n, Hong; Liu, Chengjiao; Yang, Lizhi; Zhang, Qi; Cao, Yuchen; Gu, Jingkai; Ding, Yanhua. Pharmacokinetics, Pharmacodynamics, and Tolerability of Single and Multiple Doses of Trandolapril, an Effective Angiotensin-Converting Enzyme Inhibitor, in Healthy Chinese Subjects. EUROPEAN JOURNAL OF DRUG META
41、BOLISM AND PHARMACOKINETICS, 2016, 41:373-384.42. Li, Xiaojun; Fan, Peihu; Jiang, Chunlai; Ma, Tonghui; Yu, Xianghui; Kong, Wei; Gao, Feng. High-Frequency Illegitimate Strand Transfers of Nascent DNA Fragments During Reverse Transcription Result in Defective Retrovirus Genomes. JAIDS-JOURNAL OF ACQU
42、IRED IMMUNE DEFICIENCY SYNDROMES, 2016, 72:353-362.43. Liu, Shichao; Wang, Siming; Liu, Meichen; Yang, Fei; Zhang, Hui; Liu, Shiyang; Wang, Qun; Zhao, Yu. De novo sequencing and analysis of the transcriptome of Panax ginseng in the leaf-expansion period. MOLECULAR MEDICINE REPORTS, 2016, 14:1404-141
43、2.44. Wang, Zhen; Yu, Bin; Wang, Baoming; Yan, Jingyi; Feng, Xiao; Wang, Zixuan; Wang, Lizheng; Zhang, Haihong; Wu, Hui; Wu, Jiaxin; Kong, Wei; Yu, Xianghui. A novel capsid-modified oncolytic recombinant adenovirus type 5 for tumor-targeting gene therapy by intravenous route. ONCOTARGET, 2016, 7:472
44、87-47301.45. Ma, Heran; Liu, Rui; Zhao, Ziyuan; Zhang, Zhixian; Cao, Yue; Ma, Yudan; Guo, Yi; Xu, Li. A Novel Peptide from Soybean Protein Isolate Significantly Enhances Resistance of the Organism under Oxidative Stress. PLOS ONE, 2016, 11:-.e015993846. Liu, Shiyang; Guo, Yuming; Wang, Jing; Zhu, Ha
45、i; Han, Yuqing; Jin, Mingji; Wang, Jun; Zhou, Congya; Ma, Junfeng; Lin, Qingcong; Wang, Zhaoyi; Meng, Kun; Fu, Xueqi. A novel anticancer agent SNG1153 inhibits growth of lung cancer stem/progenitor cells. ONCOTARGET, 2016, 7:45158-45170.47. Yin Juxin; Li Zuhong; Mu Ying; Lu Shaowu; Luo Guimin. Tripe
46、ptide Containing Selenium with Glutathione Peroxidase Activity. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2016, 37:1302-1306.48. Jiao Jing; Yang Xue; Jin Lanna; Gao Jian; Zhou Yang; Xiao Yazhong; Zhang Yingjiu. Conservative and Variability of the Important Functional Sites in a Laccase from
47、Bacillus Subtilis. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2016, 37:1320-1327.49. Zhang, Jing; Tian, Yang; Yan, Liang; Zhang, Guanghui; Wang, Xiao; Zeng, Yan; Zhang, Jiajin; Ma, Xiao; Tan, Yuntao; Long, Ni; Wang, Yangzi; Ma, Yujin; He, Yuqi; Xue, Yu; Hao, Shumei; Yang, Shengchao; Wang, Wen
48、; Zhang, Liangsheng; Dong, Yang; Chen, Wei; Sheng, Jun. Genome of Plant Maca (Lepidium meyenii) Illuminates Genomic Basis for High-Altitude Adaptation in the Central Andes. MOLECULAR PLANT, 2016, 9:1066-1077.50. Jian, Hui; Wang, Yingwu; Bai, Yan; Li, Rong; Gao, Renjun. Site-Specific, Covalent Immobi
49、lization of Dehalogenase ST2570 Catalyzed by Formylglycine-Generating Enzymes and Its Application in Batch and Semi-Continuous Flow Reactors. MOLECULES, 2016, 21:-.89551. Tian, Yuantong; Zhao, Lijing; Wang, Ye; Zhang, Haitao; Xu, Duo; Zhao, Xuejian; Li, Yi; Li, Jing. Berberine inhibits androgen synthesis by interaction with aldo-keto reductase 1C3 in 22Rv1 prostate cancer cells. ASIAN JOURNAL OF ANDROLOGY, 2016, 18:607-612.52. Yang, Zhichao; Sun, Lingxia; Liang, Chunsu; Xu, Yongwei; Cao, Jianming; Yang, Yan; Gu, Jingkai. Simultaneous quantitation of the diastereoisomers of scholarisine
