1、amoxicillin granulesamoxilin keli2s5r6r-33-6-r-2-2-4-7-4-1-3.2.0-2- c16h19n3o5s3h2o 419.46-1. 2. 3. 4. 5. 6. -60ml5ml125mg0.5g6814 g2040mg/kg81330mg/kg1211030ml/120.250.5 g10 ml/240.250.5g1. 2. -3. 4. 5. 6. -1. 2. 1. 2. 3. benedictfehling4. 1 -2 10-1. 2. 51250mg/kgc16h19n3o5s0.125g 2amoxicillin caps
2、ulesamoxilin jiaonang(2s,5r,6r)-3,3-6-(r)-(-)-2-2-(4-)-7-4-1-3.2.0-2- c16h19n3o5s3h2o419.46123456-0.5 g0.5g6814g820?40mg/kg81330mg/kg12110?30ml/120.25?0.5g1/2?110ml/240.25?0.5g12-3456-1234beneditfehling5(1)-(2)10-1. 2. 51250 mg/kg75%?90%,0.25g0.5g(cmax)3.5?5.0mg/l5.5?7.5mg/l,1?20.5g2?360.52mg/l0.53m
3、g/l11mg/l3.5mg/l1g1?26.2mg/l1g20.1?1.5mg/l0.9%?21.1%1/4?1/3-17%?20%(t1/2)11.324%33%645%68%-7112224336448482010h2000326312h21023908amoxicillin 1 2 3 4 56-1. 2. 1. 2. -3. 4. 5. 6. -0.25g(c16h19n3o5s)0.5g6814g2040mg/kg81 330mg/kg1211030ml/120.250.5g10ml/240.250.5g1. 2. 3 4 beneditfehling 5 (1)- (2)2 am
4、oxicillin cranulesamoxilin keli(2s,5r,6r)-3,3- 6-(r)-(-)-2-2-(4-)-7-4-1-3.2.0-2-c16h19n3o5s3h2o419.46-1. 2. 3. 4. 5. 6. -c16h19n3o5s 0.125g2040mg/kg8150mg330mg/kg 0.125g/ 3 0.4 3 0.5 13 135 1.5510 210 234681321. 2. -3. 4. 5. 6. -1241-231030ml/120.250.5g10ml/240.250.5g10 -1. 2. 51250mg/kg2s5r6r-3.3-6
5、-(r)-(-)-2-2-(4-)-7-4-1-3.2.0-2-120.5g4684g2040mg/kg850mg2/5330mg/kg1030ml/120.250.5g2-410ml/240.250.5g242r3s4r5r8r10r11r12s13s14r-13-26-3-c-3-o-l-2-3410-3568101214-11-346-3-d-1-6-15-1. 2. 3. -4. -5. 50s-12-1.0g10.5g250.25g0.5g3110mg/kg0.5g255mg/kg0.25g/kg2515-25kg0.2g0.1g26-35kg0.30.1536-45kg0.4g0.2g a-a-a-a :660%2h
