1、ONE lesson Ive learned while writing about fitness is that few things impinge on an active life as much as writing about fitness all that time spent hunched before a computer or puzzling over scientific journals, the countless hours of feckless, seated procrastination. While writing about the benefi
2、ts of exercise, my muscles slackened. Fat seeped insidiously into my blood, liver and ventricles. Stupor infiltrated my brain. We all know by now that being inactive is unhealthy. But far too many of us think that being inactive is something that happens to other people. Studies of daily movement pa
3、tterns, though, show that your typical modern exerciser, even someone who runs, subsequently sits for hours afterward, often moving less over all than on days when he or she does not work out. The health consequences are swift, pervasive and punishing. In a noteworthy recent experiment conducted by
4、scientists at the University of Massachusetts and other institutions, a group of healthy young men donned a clunky platform shoe with a 4-inch heel on their right foot, leaving the left leg to dangle above the ground. For two days, the men hopped about using crutches (and presumably gained some resp
5、ect for those people who regularly toddle about in platform heels). Each mans left leg never touched the ground. Its muscles didnt contract. It was fully sedentary. After two days, the scientists biopsied muscles in both legs and found multiple genes now being expressed differently in each mans two
6、legs. Gene activity in the left leg suggested that DNA repair mechanisms had been disrupted, insulin response was dropping, oxidative stress was rising, and metabolic activity within individual muscle cells was slowing after only 48 hours of inactivity. In similar experiments with lab animals, casts
7、 have been placed on their back legs, after which the animals rapidly developed noxious cellular changes throughout their bodies, and not merely in the immobilized muscles. In particular, they produced substantially less of an enzyme that dissolves fat in the bloodstream. As a result, in animals and
8、 humans, fat can accumulate and migrate to the heart or liver, potentially leading to cardiac disease and diabetes. To see the results of such inactivity, scientists with the National Cancer Institute spent eight years following almost 250, 000 American adults. The participants answered detailed que
9、stions about how much time they spent commuting, watching TV, sitting before a computer and exercising, as well as about their general health. At the start of the study, none suffered from heart disease, cancer or diabetes. But after eight years, many were ill and quite a few had died. The sick and
10、deceased were also in most cases sedentary. Those who watched TV for seven or more hours a day proved to have a much higher risk of premature death than those who sat in front of the television less often. (Television viewing is a widely used measure of sedentary time.) Exercise only slightly lessen
11、ed the health risks of sitting. People in the study who exercised for seven hours or more a week but spent at least seven hours a day in front of the television were more likely to die prematurely than the small group who worked out seven hours a week and watched less than an hour of TV a day. If th
12、ose numbers seem abstract, consider a blunt new Australian study. In it, researchers determined that watching an hour of television can snip 22 minutes from someones life. If an average man watched no TV in his adult life, the authors concluded, his life span might be 1.8 years longer, and a TV-less
13、 woman might live for a year and half longer than otherwise. So I canceled our cable, leaving my 14-year-old son staggered. Id deprived him of his favorite shows on The Food Network, a channel that, combined with sitting, explains much about the American waistline. (Thankfully, my son is blessed wit
14、h his fathers lanky, string-bean physique.) I also conduct more of my daily business upright. In an inspiring study being published next month in Diabetes Care, scientists at the Baker IDI Heart and Diabetes Institute in Melbourne, Australia, had 19 adults sit completely still for seven hours or, on
15、 a separate day, rise every 20 minutes and walk leisurely on a treadmill (handily situated next to their chairs) for two minutes. On another day, they had the volunteers jog gently during their two-minute breaks. When the volunteers remained stationary for the full seven hours, their blood sugar spi
16、ked and insulin levels were out of whack. But when they broke up the hours with movement, even that short two-minute stroll, their blood sugar levels remained stable. Interestingly, the jogging didnt improve blood sugar regulation any more than standing and walking did. What was important, the scien
17、tists concluded, was simply breaking up the long, interminable hours of sitting. Equally beguiling, at least for me, since Im shallow, were results from experiments at the University of Massachusetts showing that when volunteers stood all day nothing else; no walking or jogging; just standing they b
18、urned hundreds more calories than when they sat for the same period of time. So every 20 minutes or so, I now rise. I dont have a desk treadmill; my office is too small, and my budget too slim. But I prop my papers on a music stand and read standing up. I prowl my office while I talk on the phone. (
19、I also stand on one foot when I brush my teeth at night, which has little to do with reducing inactivity but may be one of the more transformative actions Ive picked up from researching fitness. My balance and physical confidence have improved, and my husband is consistently amused, which is not a b
20、ad foundation for marital health.) I run for three or four miles most days, too, and grunt through 20 push-ups most mornings. There are health and fitness benefits from endurance and weight training that standing up cant match. In particular, aerobic workouts have been shown to improve brainpower, a
21、nd I shudder to imagine the state of my memory if I didnt run. But Im not planning any marathons (been there, done that, walked down stairs backward for days). I want foundational health. I want my insulin levels in check and my fat-fighting enzymes robust. I have plans for those extra 18 months of life span that not sitting might provide. The “Phys Ed” columnist for The New York Times and the author of a new book on science and exercise, “The First 20 Minutes.”
