1、Department of Microbiology, Harbin Medical UniversityMedical MicrobiologyDepartment of Microbiology, HMUDepartment of Microbiology, Harbin Medical University第三篇 医学相关病毒第31章 肠道感染病毒Gastrointestine-Infected Viruses微生物学教研室 钟照华Department of Microbiology, Harbin Medical University教学大纲掌握内容肠道病毒种类及共同特性脊髓灰质炎病毒
2、主要生物学性状、致病性、微生物学检查法及防治原则柯萨奇病毒分组、分型及致病性 熟悉内容埃可病毒、肠道病毒70型、肠道病毒71型的致病性 Department of Microbiology, Harbin Medical University问题肠道病毒有哪些？是不是肠道感染的所有病毒都称为肠道病毒？简要说明肠道病毒的特性脊髓灰质炎病毒的传播途径、致病机制是什么？如何预防脊灰？ B组柯萨奇病毒的致病有何特点？ ECHO病毒、轮状病毒、杯状病毒、小圆结构病毒分别与哪些疾病有关？Department of Microbiology, Harbin Medical UniversityGroups
3、and Serotypes Picornaviridae（小RNA病毒科） At least 71 serotypes, divided into 4 subgroupsPolioviruses （脊髓灰质炎病毒）Coxsackie viruses（柯萨奇病毒）Echoviruses（埃可病毒）New enteroviruses（新肠道病毒） more recently, new enteroviruses subtype have been allocated sequential numbers (68-71)Department of Microbiology, Harbin Medic
4、al UniversityEnteroviruses SerotypesDepartment of Microbiology, Harbin Medical UniversityMorphology27nm, icosahedral symmetry, no envelopeDepartment of Microbiology, Harbin Medical UniversityEnterovirus structureSurface cleft attachment to cellular receptors:Immunoglobulin superfamily, integrins, ICAM-1Department of Microbiology, Harbin Medical UniversityDepartment of Microbiology, Harbin Medical University
