1、Clinical practice guidelines for antimicrobial prophylaxis in surgery外科抗菌薬予防臨床実践,聖医科大学横浜市西部病院小田恵子, 塚原歩, 小倉佑太野村悠, 北野夕佳,Am J Health-Syst Pharm. 2013;70:195-283,背景,外科手術予防的抗菌薬投与, 適切行, 手術部位感染予防方法大変有効手段.術前, 術中, 術後抗菌薬選択, 投与量適正化必要.,目的, 臨床的証拠問題点基SSI防止, 実践者合理的、安全効果的抗菌薬使用標準化提供目的.抗菌薬予防感染防止意味, 1次予防, 2次予防, 根絶1次予防
2、初感染防止意味, 2次予防存在感染再発再活性防止意味.根絶感染発症防止保菌微生物駆逐事意味.1次予防焦点., ASHP(American Society of Health-System Pharmacists)IDSA(Infection Diseases Society of America)SIS(Surgical Infection Society)SHEA(Society for Healthcare Epidemiology of America)作成.,信憑性,分類,Level (evidence from large, well conducted, randomized, c
3、ontrolled clinical trials or meta-analysis)Level (evidence from small, well conducted, randomized, controlled clinical trials)Level (evidence from well conducted cohort study)Level (evidence from well conducted case control studies)Level (evidence from uncontrolled studies that were not well conduct
4、ed) Level (conflicting evidence that tends to favor the recommendation)Level (expert opinion or data extrapolated from evidence for general principles and other procedure),推奨,各論,抗菌薬推奨投与量時間,消化器,Recommendation for Surgical Antimicrobial Prophylaxis,Recommendation for Surgical Antimicrobial Prophylaxis
5、,Recommendation for Surgical Antimicrobial Prophylaxis,Recommendation for Surgical Antimicrobial Prophylaxis,頭頸部,Recommendation for Surgical Antimicrobial Prophylaxis,脳神経外科整形外科,Recommendation for Surgical Antimicrobial Prophylaxis,Recommendation for Surgical Antimicrobial Prophylaxis,産婦人科,眼科,Recomme
6、ndation for Surgical Antimicrobial Prophylaxis,循環器,Recommendation for Surgical Antimicrobial Prophylaxis,胸腔,Recommendation for Surgical Antimicrobial Prophylaxis,血管系,Recommendation for Surgical Antimicrobial Prophylaxis,移植,Recommendation for Surgical Antimicrobial Prophylaxis,泌尿器,Recommendation for Surgical Antimicrobial Prophylaxis,形成外科,Recommendation for Surgical Antimicrobial Prophylaxis,
