急性心肌梗塞治疗的进展急性心肌梗塞治疗的进展急性心肌梗塞治疗的目标 : 缩小梗塞面积 保护心功能 防治併发症 降低死亡率心肌梗塞治疗的关键:迅速、完全、持续开通梗塞相关血管一、再灌注治疗急性心肌梗塞的再灌注治疗 :溶栓治疗THROMBOLYTIC THERAPY Rationale- atherosclerotic plaque rupture; - thrombus formation;- total or subtotal occlusion;- slow spontaneous lysis;- fibrinolysisISIS-2试验The ISIS-2 collaborative group. Lancet 1988; ii: 34960 溶栓是最佳选择急性心肌梗塞治疗的进 展Thrombolytic therapywell documented benefit from thrombolytic therapy ISIS GUSTO GISSI SAMI-ECSG TAMI WWICST ASSET APSAC AMIS EMIP