1、CPAP的治疗常见问题及对策无创通气在睡眠呼吸疾病的应用天津医科大学总医院呼吸科 陈宝元打 鼾 OSA上气道狭窄和阻塞的示意图在应用 CPAP后气道大小的变化u “ 气流支撑机制 ” ，防止气道塌陷u 增加肺容量，间接扩张上呼吸道。u 刺激上气道的压力及机械性感受器，使上气道扩张肌的张力增加。u 消除局部组织水肿，减小咽侧壁的厚度 u 提高呼吸中枢对低氧及高 CO2的敏感性，改善呼吸调节功能。 气道正压无创通气技术治疗机制FlowPressureVolumeCPAP 1981FlowPressureVolumeBiPAP 1991BILEVEL ModeExspirationInspirati
2、on InspirationPressureTimeBILEVEL S BILEVEL ST BILEVEL T BILEVEL SBILEVEL S (Spontaneous) The system switches between the prescribed pressures EPAP and IPAPPressureTimeFlowThe comfort Therapy Mode Developed for reduction of respiration work For prevention of snoring obstructive sleep apnea Inspiration ExspirationNasal FlowCPAP-Pressure Auto-CPAP FOT,Flow,SnoringArtifact detectionSignalsEvents Central eventsVolume ContourObstructive events Severe Obstructions Slight Obstructions Incipient ObstructionsFlow SnoringFOTPressure AdjustmentPressure reactionp Event
