1、Medical MicrobiologyDepartment of Microbiology, HMUDepartment of Microbiology, Harbin Medical University第二篇 致病性细菌第 14章 埃希菌属Escherichia微生物学教研室 张文莉Department of Microbiology, Harbin Medical University教学大纲n 熟悉u肠道杆菌的共同特征及分类u致病性大肠埃希菌的种类和致病机制n 掌握u大肠埃希菌的卫生细菌学检查及其意义n 了解u大肠埃希菌的微生物学检查法Department of Microbiolo
2、gy, Harbin Medical University问题n 大肠埃希菌与人类健康的关系如何？n 肠道杆菌的共同特征？Department of Microbiology, Harbin Medical University形态染色n 0.4-0.7m 1-3m n 短杆菌n 革兰染色阴性n 有鞭毛n 有菌毛Department of Microbiology, Harbin Medical UniversityDepartment of Microbiology, Harbin Medical University培养特性与生化反应n 兼性厌氧n 营养要求不高n 生化反应活泼，发酵多种糖
3、类n 绝大多数发酵乳糖n IMViC试验结果为 + + - -Department of Microbiology, Harbin Medical University大肠埃希菌于普通营养平板培养生长的菌落Department of Microbiology, Harbin Medical University抗原结构n O抗原：菌体抗原n H抗原：鞭毛抗原n K抗原：荚膜抗原n O111： K58： H2Department of Microbiology, Harbin Medical University复杂的抗原构造Department of Microbiology, Harbin Medical University
