1、CLSI AST Standards January 2012v M100-S22 Tables (2012)*v M02-A11 Disk Diffusion Method (2012)*v M07-A9 MIC Method (2012)*v M11-A7 Anaerobe MIC Testing (2007)3M100-S22Partial Table of ContentsM100-S22. Page 9.4更新的更新的的总结的总结 M100-S22. Page 13.52012主要变化v 肠杆菌科 修订 厄他培南 折点 增加 环丙沙星 折点(伤寒沙门菌和胃肠外沙门菌)v 绿脓杆菌 降
2、低 哌拉西林、哌拉西林 /他唑巴坦、替卡西林、替卡西林 /克拉维酸 折点 降低 亚胺培南、美罗培南折点;增加多利培南折点v 葡萄球菌 增加金葡菌青霉素抑菌圈周边试验检测( penicillin disk zone edge test) -内酰胺酶产生6M100-S22. P222010年后折年后折点变化过程点变化过程7CLSI Breakpoint Additions / Revisions Since 2010Antimicrobial Agent Date of Revision* (M100 version)CommentsEnterobacteriaceae Aztreonam Jan
3、uary 2010 (M100-S20)Cefazolin January 2010 (M100-S20)January 2011 (M100-S21)Breakpoints were revised twice since 2010Cefotaxime January 2010 (M100-S20)Ceftazidime January 2010 (M100-S20)Ceftizoxime January 2010 (M100-S20)Ceftriaxone January 2010 (M100-S20)Doripenem June 2010 (M100-S20U) No previous
4、CLSI breakpoints for doripenemErtapenem June 2010 (M100-S20U)January 2012 (M100-S22)Breakpoints were revised twice since 2010.Imipenem June 2010 (M100-S20U)Meropenem June 2010 (M100-S20U)Cipro Salmonella only January 2012 (M100-S22)CLSI Breakpoint Additions / Revisions Since 2010Antimicrobial Agent
5、Date of Revision* (M100 version)CommentsPseudomonas aeruginosaPiperacillin-tazobactam January 2012 (M100-S22)Ticarcillin-clavulanate January 2012 (M100-S22)Ticarcillin January 2012 (M100-S22)Piperacillin January 2012 (M100-S22)单击此处编辑母版标题样式单击此处编辑母版副标题样式* 8肠杆菌科:碳靑霉烯类美国碳靑霉烯类耐药肠杆菌科( CRE)的分布黄色: KPC酶;蓝点: IMP、 VIM黄点: NDM