Overview of clinical studies evaluating different cell types Early Late Hypothesis: TM auguments angiogenic potential of EPC EndoCult EGM2 PBMC HAEC Day 7 Day 7 Day 21Day 21 P 0.05 Ctrl TMD1 TMD23 TMD123 Ctrl TMD123TMD23 TMD1 Introduction Fold Ctrl TMD23 MMP2 MMP9 Percentage (%) Ctrl TMD23 Percentage (%) MMP2 MMP9 Erk P38 PErk PP38 (Min) 0 10 30 120 Akt PAkt GAPDH 0 10 30 120 Grou p Osmoti c pump Artery ligation Injected cells 1 PBS + Saline 2 PBS + Early EPC 3 TMD23 + Saline 4 TMD23 + E
