人类疱疹病毒,Humanherpesviruses,ContainsseveralofthemostimportanthumanpathogensAspectrumofdiseasesLifelongpersistentinfectionPeriodicreactivation,Mainproperties,Virion:spherical,150-200nmcore+capsid+envelopedsDNA,encodesatleast100proteins35proteinsstructureofvirusReplication:InthenucleusBudfromnuclearmembraneEarlyreplicationandlatereplication,CPE:apartfromEBV,otherscancauseCPEincellcultureFormofinfectionReplicationinfection:primary,reactivatedLatentinfectionCongenitalinfection(先天性感染)Celltransformat