1、,SciFinder数据库使用培训,南京林业大学2013.04,SciFinder Web培训,SciFinder Web介绍SciFinder Web中的内容SciFinder Web特色功能SciFinder Web中的检索SciFinder Web中的常规检索举例SciFinder Web中的其他应用举例SciFinder Web的注册和常见问题,2,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,美国化学文
2、摘社Chemical Abstract Service,3,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,ACS的分支机构，创立于1907年致力于跟踪、索引并提炼全球化学相关的科技文献信息最先创立了纸本化学文摘Chemical Abstracts TM总部位于俄亥俄州的哥伦布市,1300名员工，精通50多种语言。关注索引上万种期刊和63家专利客户覆盖全球1900所高校、500强公司以及所有主要的专利局。,SciF
3、inder Web中的几个主要数据库,4,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,CAplusSM 涵盖了上万种期刊及63个专利发行机构专利,5,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,India (IN),China
4、(CN),Singapore (SG),Republic of Korea (KR),Philippines (PH),Taiwan (TW),Hong Kong (HK),Japanese Patent Office (JPO),CAplusSM中的索引词帮助解决各种描述歧义问题,文献检索过程中经常遇到很多同义词、近义词、单复数、不同时态的情况，科研人员常常花费大量的时间进行检索式的编辑；全球科研人员对同一概念的描述，受语种习惯，教育背景的不同而不同SciFinder Web中的Index term是一种标准化的索引词，配合智能化的检索模式，保证检索的全面性,6,CAS is a divis
5、ion of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,CAS REGISTRYSM 是化学物质信息的“黄金标准”,7,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,CASREACT 是检索化学反应最权威的来源,8,CAS is a division of the Am
6、erican Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,CASREACT是世界上最大的，更新速度最快的反应数据库,MARPAT 全球专利文献中的Markush结构库,9,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,MARPAT帮助最大程度的找到结构相关专利文献,SciFinder Web登陆界
7、面http:/scifinder.cas.org http:/origin-scifinder.cas.org,10,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,输入SciFinder帐号和密码,SciFinder Web登陆后主界面,11,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical S
8、ociety. All rights reserved.,文献，物质，反应检索入口，默认开始检索文献,可用的检索方法,保存过的结果集,邮件提醒结果集,检索完，请点击退出,提纲,SciFinder Web介绍SciFinder Web中的内容SciFinder Web特色功能SciFinder Web中的检索SciFinder Web中的常规检索举例SciFinder Web中的其他应用举例SciFinder Web的注册和常见问题,12,CAS is a division of the American Chemical Society. Copyright 2011 American Che
9、mical Society. All rights reserved.,SciFinder Web特色功能根据引文排序,13,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,依据被引次数排序,SciFinder Web特色功能Quick View (Reference),14,CAS is a division of the American Chemical Society. Copyright 2011 Ame
10、rican Chemical Society. All rights reserved.,快速查看文献的摘要、物质、图片信息,SciFinder Web特色功能物质的靶标和生物活性,15,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,在物质详细信息栏，可以查询到物质的生物活性信息和靶标信息,SciFinder Web特色功能依据物质性质检索,16,CAS is a division of the American
11、 Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,性质检索，可通过物质的熔沸点、分子量等实验和预测性质查看物质信息,SciFinder Web特色功能SciPlanner合成路线设计,17,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,SciFinder Web特色功能反应过程的获取,18,CAS i
12、s a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,SciFinder中的部分源自期刊和专利中的反应，提供了反应过程信息，使得科研工作者不需要阅读原文，就可以获得对应的反应历程。,提纲,SciFinder Web介绍SciFinder Web中的内容SciFinder Web特色功能SciFinder Web中的检索SciFinder Web中的常规检索举例SciFinder Web中的其他应用举例SciFinder Web的注
13、册和常见问题,19,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,Scifinder web-文献检索,案例：天然产物中的抗肿瘤物质 Natrual products of anti-tumor,20,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights re
14、served.,主题词之间用（of, with, in )等介词连接,主题检索候选项,21,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,“Concept”表示做了同义词的扩展，保证文献检索的全面性,Scifinder web文献检索结果,22,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical
15、Society. All rights reserved.,全文链接,文献分析和限定工具,物质及被引用的文献链接,工具栏,文献结果的处理,23,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,如何在大量文献中发现最关健的信息？,文献分析,12种分析方法，可以帮助我们逐步了解信息需求,Index term 索引词分析,24,CAS is a division of the American Chemical Soci
16、ety. Copyright 2011 American Chemical Society. All rights reserved.,快速了解文献研究的主要内容，精选文献,构效关系研究,Publication Year 出版年限分析,25,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,出版年：了解该领域的研究历史和发展,Natural Order出版年限排序,天然产物中抗肿瘤药物研究趋势图,26,CAS is
17、a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,组织机构分析：了解潜在的竞争者、合作伙伴,作者分析：发现本领域、课题的主要研究人员，以及同行评审专家,来源期刊分析：发现相关的学术期刊，快速定位投稿期刊,文献的限定Refine,27,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All ri
18、ghts reserved.,如何获得综述类、临床研究方面的文献？,文献限定,利用“document type”可以筛选综述、临床研究、论文、专利等特定类型的文献,获得一千多篇综述、临床研究的文献,28,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,Citing References引文索引排序,Categorize 系统分类功能,29,CAS is a division of the American Chem
19、ical Society. Copyright 2011 American Chemical Society. All rights reserved.,快速筛选不同学科的相关文献,Categorize系统分析,30,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,合成化学,纯化物质,生物碱,31,CAS is a division of the American Chemical Society. Copyrig
20、ht 2011 American Chemical Society. All rights reserved.,HPLC、提取、NMR用于文献的筛选,分析化学,分析方法,Categorize 系统分析,文献结果的查看、保存,32,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,历史导航条，返回原先的检索界面,点击标题，查看详细信息,33,CAS is a division of the American Chemi
21、cal Society. Copyright 2011 American Chemical Society. All rights reserved.,摘要信息,一键获得物质、反应、参考文献等相关信息,34,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,重要概念索引,物质信息,文献结果保存,35,CAS is a division of the American Chemical Society. Copyrig
22、ht 2011 American Chemical Society. All rights reserved.,使用Export将结果输出,Citation manager: 保存成RIS格式，用于导入EndNote等文献管理工具Offline Review:保存过成PDF，RTF格式，用于脱机浏览,文献检索小结,主题检索时，使用介词作为连接尽量选择包含Concept和Closed Associated with的候选项通过SciFinder 的Analyze/Refine功能来缩小检索的范围尝试将不同的Analyze/Refine功能组合起来用，会有更多的收益使用Categorize可以让系
23、统来实现自动分类更多细节化内容，请参考 is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,Scifinder web 物质检索,37,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,化学结构检索Markush检索分子式检索性质检索物质标示符检索,
24、双击打开绘图面板,38,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,SciFinder结构绘制工具,CAS号直接转换为化学结构,39,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,紫杉醇CAS号： 33069-62-4,40,CA
25、S is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,精确结构检索亚结构检索相似结构检索,Substance identifier 物质标示符检索,41,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,检索紫杉醇（taxol，33069-62-4
26、）的理化性质及其生物活性,可以输入物质的名称，CA号，俗名，商品名，来进行检索,物质检索结果,42,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,物质的实验性质,一键获得参考文献、反应、商品信息,物质的角色分类(CAS Role ),43,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Soc
27、iety. All rights reserved.,按照CAS Role分类的专利、非专利文献列表。对某类文献感兴趣，仅需点击交叉处的 即可方便快捷地获取。,获得73篇紫杉醇在分析化学研究中的专利文献,生物活性标记和靶点标记,44,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,列出紫杉醇生物活性研究的分类及参考文献。比如：抗病毒、抗有丝分裂、抗感染等。,利用物质中的靶点标记功能，快速了解紫杉醇在不同靶点中的研究
28、情况。,物质的合成信息,45,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,提纲,SciFinder Web介绍SciFinder Web中的内容SciFinder Web特色功能SciFinder Web中的检索SciFinder Web中的常规检索举例SciFinder Web中的其他应用举例SciFinder Web的注册和常见问题,46,CAS is a division of the American
29、Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,聚合物检索,只知道起始原料的聚合物知道结构重复单元（SRU）的聚合物,47,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,聚合物检索,只知道起始原料的聚合物检索检索策略：组分间用点分开，每个组分采用Hill排序，括号外用x表示,48,CAS is a d
30、ivision of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,(C4H6O2.C2H3Cl.C2H3F)x,聚合物检索,知道结构重复单元（SRU）的聚合物检索检索策略：采用Hill排序，括号外用n表示,49,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,(C12H22
31、N2O2)n,注意区分n 与x的区别,聚合物的结构检索,50,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,可以在绘图面板中将不同组分的结构绘制出来，系统会自动进行碎片检索。,聚合物检索,51,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserv
32、ed.,精确检索,聚合物,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,SciFinder中的反应定义工具,52,SciFinder中的反应检索,53,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,检索符合以下条件的氰基的还原反应,
33、SciFinder中的反应检索,54,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,Variable Only at the Specified Positions：精确反应检索Substructure of more complex structure：亚结构反应检索,反应检索结果,55,CAS is a division of the American Chemical Society. Copyright
34、2011 American Chemical Society. All rights reserved.,反应分析/限定工具,反应条件、参考文献,反应分析和限定工具,56,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,筛选经济、适用的催化剂,筛选较高收率的反应记录，协助进行工艺设计,反应分类,生物转化类反应,生物转化类反应记录,57,CAS is a division of the American Chemical Society. Copyright 2011 American Chemical Society. All rights reserved.,同位素标记显示，对位取代的苄胺在芳香胺脱氢酶的作用下反应转化率情况,Similar Reactions相似反应检索,
