传染性单核细胞增多症Infectiousmononucleosis,YongfuHuangChunxiaLiuThe4thClinicalMedicalCollegeofYangzhouUniversity,LaboratoryMedicineCentreofNantongRichHospital,JiangsuNantong226010,China,一、概述,1.定义,由EB病毒引起的一种急性或亚急性淋巴细胞良性增生的传染病。,Self-limitingdisorderoflymphoidtissuecausedbyinfectionwithEpsteinBarrvirus(infectiousmononucleosis).Characterisedbytheappearanceofmanylargelymphoblastsinthecirculation.,EB病毒(Epstein-Barrvirus,EBV),Epstein和Barr于1964年从非洲儿童恶性淋巴瘤(Burkittslymphoma)细胞培养中最早发现主要侵犯B细胞.,EBV属疱疹病毒亚科,外层有囊