恶性脑肿瘤的化学治疗,四川省肿瘤医院内科张智慧,CerebrumandCerebellum,流行病学趋势,2019(US)18,500*12,760Incidence11.47per100,000(annualrate)Adjusted5yrsurvivalrate(2019-2000)33%adults73%children2ndleadingcauseofcancerdeathsinpersons肿瘤,正常脑组织暴露化疗药物,高渗性BBB开放,Bloodbrainbarrierdisruption(BBBD)andintra-arterialmethotrexatebasedtherapyfornewlydiagnosedprimaryCNSlymphoma:TheBBBDConsortiumExperience.,2019ASCOAnnualMeetingProceedingsPartI.Vol25,No.18S,4institutions：1982-2019，177PCNSL,BBBD/IAMTX；2,469procedures,PtsCRPRORRMOS(y)MPFS(
