介入术后抗血小板治疗,一抗血小板药物作用机制和阿司匹林抵抗,不同的抗血小板药物作用机制,胶原凝血酶TXA2,阿司匹林,ADP,(纤维蛋白原受体),氯吡格雷,TXA2,ADP,双嘧达莫,磷酸二酯酶,ADP,GpIIb/IIIa,激活,COX,盐酸噻氯匹定,ADP=adenosinediphosphate,TXA2=thromboxaneA2,COX=cyclooxygenase.SchaferAI.AmJMed.1996;101:199209.,Category%ORAcuteMIAcutestrokePriorMIPriorstroke/TIAOtherhighriskCoronaryarterydisease(unstableangina,heartfailure)Peripheralarterialdisease(intermittentclaudication)222%Highriskofembolism(atrialfibrillation)Other(diabetesmellitus)Alltrials,1.0,0.5