,撤机相关性肺水肿,呼吸机-双刃剑,运用得当可救命不当运用可致命,Failingatweaningfrommechanicalventilationleadstoprolongedintubationwithitsinherentrisksofincreasedmorbidityandmortality.Identicationofthecausesofweaningfailureisimportantbecauseitcouldenablespecictherapyandperhapsshortenthedelayuntilextubation.,撤机失败定义为自主呼吸试验失败或在拔管后48小时内需重新插管，发生率达31。,撤机导致的肺水肿（WIPE）,撤机导致的肺水肿是撤机失败的一个重要原因，亦是撤机试验需面对的重要挑战！WIPE能导致入住ICU时间延长，增加病死率！,WIPE机制(Mechanisms),Thesemechanismsarecomplexandmainlyincludetheinspiratoryfallinintrathoracicpressure,the
