“隐源性”肝硬化诊断与治疗,一、肝硬化流行病学,1.03 million deaths / year,Euroasian Journal of Hepato-Gastroenterology, 2018,二、肝硬化病因,HBV or HCV decreased from 50 or more to 20 or less alcoholic liver disease or cryptogenic liver injury emerged as major cause of liver cirrhosis,Euroasian Journal of Hepato-Gastroenterology, 2018,二、肝硬化病因,隐源性肝硬化占10.6%,CLINICS, 2015,隐源性肝硬化（cryptogenic cirrhosis，CC）,定义：根据病史、实验室检查、影像学及病理等暂不能明确 诊断的肝硬化类型 过去：病毒性肝炎（HBV、HCV等）、酒精性肝病、自身免疫 性肝病等为肝硬化常见类型 现在：非酒精性脂肪性肝病和遗传代谢性肝病（wilson病）等 也
