,氟盐在骨质疏松治疗中分子生物学机制,Fluoride,physicochemical effects carbonated hydroxylapatite carbonated fluorapatite biologic effects chemical forms, doses, and exposures,Fluoride,narrow therapeutic/toxicity window 530 M biphasic actions Low dose - increase bone mass High dose - reduce bone mass genetic background,Fluoride,The stimulatory effects of sodium fluoride (NaF) on bone formation have been explained solely by its activation of osteoblasts,Wnt/-catenin signalin
