中心静脉插管相关感染,导管相关性感染: 流行病学,美国ICU每年16,000例CRBSI 病死率18% (0 35%) 每年死亡500 4,000例 每例CRBSI医疗费用$28,690 56,000 每年费用$60,000,000 460,000,000,CDC. MMWR 2002; Heiselman JAMA 1994; Dimick Arch Surg 2001,中心静脉插管相关性感染发病率,患者数n = 1,098 中心静脉插管n = 1,263 导管留置天n = 6,075 细菌定植n = 333 (26.3%) CRBSIn = 35 (2.7%) 5.9 / 1,000导管留置天,Safdar N, Maki DG. Inflammation at the insertion site is not predictive of catheter-related bloodstream infection with short-term, noncuffed central venous catheters. Crit Care Med 2002; 30: 2632-