南方医科大学声明：1. The study complied with the declaration of Helsinki and was approved by the local research ethics committee. All subjects gave written informed consent.2. All animal experimentation was approved by the St. Louis VA Animal Care Committee and conducted in conformity with the Guiding Principles for Research Involving Animals and Human Beings.3. The study was carried out with institutional review board approval. Informed consent was obtained from patients to perform for study p
