1、,Articular cartilage injury of the knee,li yan,General Information,Name :Lu x xMale18Yoccupation :acrobat,pain, swelling,immobility of right knee for 2msworsen 2ds,Chief Complaint,History of present illness,pain, immobility ,swelling of right knee for 2ms when taking exercise 2 days ago,injuried whe
2、n jumping,then the symptom became worsen,Other Medical History,past history：（-）personal history：（-）family history：（-）,Right knee: swellingFloating patella test : (+)McMurray sign : (+)Drawer test : (-),Physical Examination,Physical Examination,LameMuscle atrophy ROM:0-130,Imaging Examination,MRI,def
3、ect 2*2cm,Lab Examination,Urine RTBlood RTLiver functionRenal functionECGAll above is normal,Diagnosis,Articular cartilage injury of the knee,Surgery,Osteochondral Transplant,Result,Discussion,Function of articular cartilage:Variable load-bearing through a range of motion in functional activitiesRed
4、uce stress on the subchondral bone & minimise frictionAbsorbs load-forces up to 5x body weight,Discussion,Healing Response : PathophysiologyNo blood supplyNo lymphatic drainageNo neural elementNo immunological recognition,Discussion,Discussion,Full-thickness articular cartilage injury is notoriously
5、 difficult to be treated in the fields of orthopedics and sports medicine.,Discussion,Once destroyed, is not repairedRepair cartilage is mainly of type I collagen with poor wear characteristics,Discussion,Substitution Replacement:Osteochondral transplantsAutologous chondrocyte implantation,Discussion,Allogeneic bone and cartilage transplantation can offer a transparent cartilage with biological activity and biomechanical properties to repair full- thickness articular cartilage defects.,,Thank You !,
