1、 滤器/膜结构There are a number of key scientific principles used to accomplish the goals of CRRT. They are listed here and before we discuss the individual therapies, I would like to review them. Understanding the principles of diffusion, ultrafiltration, convection and adsorption will clarify which ther
2、apy will best produce the desired outcome whether used alone or in combination. 超滤The transport of a molecule through a membrane is governed primarily by its molecular weight. Generally, the more a molecule weighs, the larger it is in size and the more resistant it is to transport. The chart gives a
3、n indication of relative molecular weights for some of the common molecules that we are concerned with in CRRT. Molecular weights are measured in units called daltons.urea, electrolytes, creatinine - “small” moleculesvitamin B12, inulin - “middle” moleculesbeta 2, albumin - “large” molecules弥散The tr
4、ansport of a molecule through a membrane is governed primarily by its molecular weight. Generally, the more a molecule weighs, the larger it is in size and the more resistant it is to transport. The chart gives an indication of relative molecular weights for some of the common molecules that we are
5、concerned with in CRRT. Molecular weights are measured in units called daltons.urea, electrolytes, creatinine - “small” moleculesvitamin B12, inulin - “middle” moleculesbeta 2, albumin - “large” molecules对流 The transport of a molecule through a membrane is governed primarily by its molecular weight.
6、 Generally, the more a molecule weighs, the larger it is in size and the more resistant it is to transport. The chart gives an indication of relative molecular weights for some of the common molecules that we are concerned with in CRRT. Molecular weights are measured in units called daltons.urea, el
7、ectrolytes, creatinine - “small” moleculesvitamin B12, inulin - “middle” moleculesbeta 2, albumin - “large” molecules，其优点为连续性治疗，可缓慢、等渗地清除水和溶质，容量波动小，净超滤率明显低，胶体渗透压变化程度小，基本无输液限制，能随时调整液体平衡，从而一般对血流动力学影响较小，更符合生理情况连续性治疗，可缓慢、等渗地清除水和溶质，容量波动小，净超滤率明显低，胶体渗透压变化程度小，基本无输液限制，能随时调整液体平衡，从而一般对血流动力学影响较小，更符合生理情况易出现气胸、血胸、臂丛神经损伤等。
