Chapter 13Cell apoptosis 1. Extracellular cotrol of cell division, 2. cell growth, and apoptosisMitogens stimulate G1-Cdk and G1/S-Cdk activitiesPRIZED Horvitz, and Sulston share Physiology or Medicine Nobel (2002) “for their discoveries concerning genetic regulation of organ development and programmed cell death”1090 131= 959(cells)机体结构细胞增殖 细胞分化 细胞凋亡细胞信号转导染色体(DNA与蛋白质的相互作用)衰老A simplified model of one way that mitogens stimulate cell divisionHuman cells have a built-in limitation on the number of