1、猪肺炎支原体的免疫时机及疫苗的选择先灵葆雅动物保健市场技术部荣 强1Mycoplasma hyopneumoniae猪支原体肺炎(Mycoplasma pneumonia of swine MPS)Enzootic Pneumonia (EP)2M. hyo Disease猪 支原体肺炎n First isolated from pig lungs in 1965n 1965年首次在猪肺脏中分离n One of the most common and economically important diseasesn 最普遍和经济意义重大的疾病之一n A complex interaction
2、between M. hyo and other bacterial and viral infections, and poor management and ventilation.n 主要损失是支原体和其它细菌病毒的混合感染、饲养管理不善、通风不良等综合因素所致。3M. hyo Diseasen One of the primary pathogens causing Porcine Respiratory Disease Complex (PRDC)n 引起 PRDC 的原发病原之一n Affects as many as 99% of U.S. herdsn 99的美国猪群都有感染n
3、 World-wide significancen 世界范围内养猪生产中流行4M. hyo diseasen Economic effects are extremely variable between herds. n 不同猪群的经济影响差异较大n Dependent on cost of inputs, price of pigs, other diseases, etc.n 取决于投入的成本、猪价、其它疾病的情况等。n A MOVING TARGET.5M. hyo Diseasen Reduced average daily gain (ADG)n 降低日增重n Reduced fe
4、ed efficiency (FE)n 降低饲料报酬n Increased medication costsn 增加药物成本n Increased cull or light-weight pigsn 增加淘汰或低体重的猪n Etc.67M. hyo Economic Lossesn M. hyo decreased growth rate 12.7% and decreased feed efficiency by 13.8% (Pointon, et al,1985)n 肺炎支原体可降低生长率 12.7%和饲料报酬13.8%8M. hyo diseasen Transmission bet
5、ween pigs: aerosol and direct contactn 猪之间传播途径：空气和直接接触n Transmission between farms: movement of infected pigs n 猪场之间传播方式：感染猪的移动n Aerosol between farms: Britain 3.2 kmn 猪场之间传播距离： 3.2公里9M. hyo DiseaseClinical signs include:临床 症状n chronic cough (often dry or nonproductive)n 慢性咳嗽（通常是干咳）n high morbidity and low mortalityn 高发病率和低死亡率n uneven groups of pigsn 猪群内生长不整齐10
