1、 研究雄黄中砷、朱砂中汞在体内可溶性部分的含量进行价态研究，制订专属、合理的分析测定方法制订其限量标准，合理评价该类药物，保证含朱砂、雄黄中成药的安全性和有效性1) When comparing 1%HCl extractable Hg with the total Hg in the TCMs, the soluble Hg is relatively low. And, when extracted by artificial gastric juice, the soluble Hg are even lower.2) When the daily intake amounts of t
2、he TCMs are considered, the daily intake soluble Hg are lower than the JECFA recommended safety level in most of the case. (JECFA: Joint FAO/WHO Expert Committee on Food Additives ). Even the cases with relatively high Hg, the extractable level are also approaching to the safety level. The relativel
3、y high Hg is maybe because of low quality vermilion in the TCM or because of the reaction inside the TCM when developing. In one word, the extractable Hg in the TCMs can be considered safe to people. 3) Then, the vermilion in the TCMs can be considered safe for the medical purpose. 砷和汞在酸性环境下有一定的溶出，且超出有关规定，但其溶出的成分可能既是毒性性成分，也是药效成分。因此要对其进行深入研究 结论：1.砷、汞有一定程度的溶出，且超出2005年版药典的 限量标准，但可能是无毒的！？是指复合的有机物吗？不清楚，分别叙述！2.多个含朱砂的中成药中Pb含量超出2005年版药典的限量标准
